Proctitis is an inflammation of the rectum. It can cause discomfort, bleeding, and the discharge of mucus or pus.


There are many causes of proctitis. They can be grouped as follows:

Proctitis caused by STD is common in people who have anal intercourse. STDs that can cause proctitis include gonorrhea, herpes, chlamydia, and lymphogranuloma venereum.

Infections that are not sexually transmitted are less common than STD proctitis. One type of proctitis not from an STD is an infection in children that is caused by the same bacteria as strep throat.

Autoimmune proctitis is linked to diseases such as ulcerative colitis or Crohn disease. If the inflammation is in the rectum only, it may come and go or move upward into the large intestine.

Proctitis may also be caused by some medicines, radiotherapy or inserting harmful substances into the rectum.

Risk factors include:


Symptoms include:

Exams and Tests

Tests that may be used include:


Most of the time, proctitis will go away when the cause of the problem is treated. Antibiotics are used if an infection is causing the problem.

Corticosteroids or mesalamine suppositories or enemas may relieve symptoms for some people.

Outlook (Prognosis)

The outcome is good with treatment.

Possible Complications

Complications may include:

When to Contact a Medical Professional

Call your health care provider if you have symptoms of proctitis.


Safe sex practices may help prevent the spread of the disease.

Review Date: 4/24/2017
Reviewed By: Michael M. Phillips, MD, Clinical Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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