Chorionic villus sampling (CVS) is a test done on some pregnant women.
The test is done to screen your baby for genetic problems.
CVS can be done through the cervix (transcervical) or through your belly (transabdominal). Miscarriage rates are slightly higher when the test is done through the cervix.
The transcervical procedure is performed by inserting a thin plastic tube through the vagina and cervix to reach the placenta. The provider uses ultrasound images to help guide the tube into the best area and then removes a small sample of chorionic villus tissue.
The transabdominal procedure is performed by inserting a needle through the abdomen and uterus and into the placenta. Ultrasound is used to help guide the needle, and a small amount of tissue is drawn into the syringe. The sample is placed in a dish and evaluated in a laboratory. Test results take about 2 weeks.
Your health care provider will explain the procedure, its risks, and alternative procedures such as amniocentesis.
You will be asked to sign a consent form before this procedure, and you may be asked to wear a hospital gown.
The morning of the procedure, you may be asked to drink fluids and refrain from urinating. Doing so fills your bladder, which helps the doctor see where to best guide the needle.
Tell your health care provider if you are allergic to iodine or shellfish, or if you have any other allergies.
The ultrasound doesn't hurt. A clear, water-based conducting gel is applied to your skin to help with the transmission of the sound waves. A hand-held probe called a transducer is then moved over the area. In addition, your health care provider may apply pressure on your abdomen to find the position of your uterus.
The cleansing solution will feel cold at first and may irritate your skin if not washed off after the procedure.
Some women say the vaginal approach feels like a Pap smear with some discomfort and a feeling of pressure. There may be a small amount of vaginal bleeding following the procedure.
An obstetrician can perform this procedure in about 5 minutes, after preparation.
Some people have a greater risk than others of passing on genetic disorders to their children. A common example is pregnant women over 35.
The test is used to identify any genetic disease in your unborn baby.
Genetic counseling is recommended prior to the procedure. This will allow you to make an unhurried, informed decision about options for prenatal diagnosis.
It can be done sooner in pregnancy than amniocentesis, usually about 10 to 12 weeks of pregnancy.
Chorionic villus sampling does not detect:
A normal result means there are no signs of any genetic defects in the developing baby. However the test could miss some genetic defects.
This test can help detect more than 200 disorders. Abnormal results may be due to a number of different genetic conditions, including:
Talk to your doctor about the meaning of your specific test results.
The risks of CVS are only slightly higher than those of an amniocentesis.
Possible complications include:
When CVS is performed after 9 weeks gestational age, limb problems are no more frequent than in pregnancies without such testing.
If your blood is Rh negative, you may receive RhoGAM to prevent Rh incompatibility.
You will receive a follow-up ultrasound 2 to 4 days after the procedure to make sure the pregnancy is proceeding normally.
Reviewed By: A.D.A.M. Health Solutions, Ebix Inc., Editorial Team: David Zieve, MD, MHA, and David R. Eltz. Previously reviewed by Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Bellevue, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine (5/31/2012)