Estradiol blood test


An estradiol test measures the amount of a hormone called estradiol in the blood. Estradiol is one of the main types of estrogens.

How the Test is Performed

A blood sample is needed.

How to Prepare for the Test

Your health care provider may tell you to temporarily stop taking certain medicines that may affect test results. Be sure to tell your provider about all the medicines you take. These include:

DO NOT stop taking any medicine before talking to your doctor.

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.

Why the Test is Performed

In women, most estradiol is released from the ovaries and adrenal glands. It is also released by the placenta during pregnancy. Estradiol is also produced in other body tissues, such as skin, fat, cells bone, brain, and liver. Estradiol plays a role in:

In men, a small amount of estradiol is mainly released by the testes. Estradiol helps prevent sperm from dying too early.

This test may be ordered to check:

The test may also be ordered to check if:

The test may also be used to monitor people with hypopituitarism and women on certain fertility treatments.

Normal Results

The results may vary, depending on the person's gender and age.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test result.

What Abnormal Results Mean

Disorders that are associated with abnormal estradiol results include:


Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight, but may include:

Review Date: 7/17/2017
Reviewed By: Cynthia D. White, MD, Fellow American College of Obstetricians and Gynecologists, Group Health Cooperative, Bellevue, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

This information should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. © 1997- 2007 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.