All content below is taken in its entirety from the CDC Influenza Live, Intranasal Flu Vaccine Information Statement (VIS): www.cdc.gov/vaccines/hcp/vis/vis-statements/flulive.html.
CDC review information for Live, Intranasal Influenza VIS:
Content source: National Center for Immunization and Respiratory Diseases.
Why get vaccinated?
Influenza ("flu") is a contagious disease that spreads around the United States every year, usually between October and May.
Flu is caused by influenza viruses, and is spread mainly by coughing, sneezing, and close contact.
Anyone can get flu. Flu strikes suddenly and can last several days. Symptoms vary by age, but can include:
Flu can also lead to pneumonia and blood infections, and cause diarrhea and seizures in children. If you have a medical condition, such as heart or lung disease, flu can make it worse.
Flu is more dangerous for some people. Infants and young children, people 65 years of age and older, pregnant women, and people with certain health conditions or a weakened immune system are at greatest risk.
Each year thousands of people in the United States die from flu, and many more are hospitalized.
Flu vaccine can:
Live, attenuated flu vaccine - LAIV, Nasal Spray
A dose of flu vaccine is recommended every flu season. Children younger than 9 years of age may need 2 doses during the same flu season. Everyone else needs only 1 dose each flu season.
The live, attenuated influenza vaccine (called LAIV) may be given to healthy, non-pregnant people 2 through 49 years of age. It may safely be given at the same time as other vaccines.
LAIV is sprayed into the nose. LAIV does not contain thimerosal or other preservatives. It is made from weakened flu virus and does not cause flu.
There are many flu viruses, and they are always changing. Each year LAIV is made to protect against 4 viruses that are likely to cause disease in the upcoming flu season. But even when the vaccine doesn't exactly match these viruses, it may still provide some protection.
Flu vaccine cannot prevent:
It takes about 2 weeks for protection to develop after vaccination, and protection lasts through the flu season.
Some people should not get this vaccine
Some people should not get LAIV because of age, health conditions, or other reasons. Most of these people should get an injected flu vaccine instead. Your healthcare provider can help you decide.
Tell the provider if you or the person being vaccinated:
Sometimes LAIV should be delayed. Tell the provider if you or the person being vaccinated:
Risks of a vaccine reaction
With any medicine, including vaccines, there is a chance of reactions. These are usually mild and go away on their own, but serious reactions are also possible.
Most people who get LAIV do not have any problems with it. Reactions to LAIV may resemble a very mild case of flu.
Problems that have been reported following LAIV:
Children and adolescents 2-17 years of age:
Adults 18-49 years of age:
Problems that could happen after any vaccine:
As with any medicine, there is a very small chance of a vaccine causing a serious injury or death.
The safety of vaccines is always being monitored. For more information, visit: www.cdc.gov/vaccinesafety.
What if there is a serious reaction?
What should I look for?
What should I do?
VAERS does not give medical advice.
The National Vaccine Injury Compensation Program
The National Vaccine Injury Compensation Program (VICP) is a federal program that was created to compensate people who may have been injured by certain vaccines.
Persons who believe they may have been injured by a vaccine can learn about the program and about filing a claim by calling 1-800-338-2382 or visiting the VICP website at www.benefits.gov/benefits/benefit-details/641. There is a time limit to file a claim for compensation.
How can I learn more?
Reviewed By: David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.