Hereditary elliptocytosis

Definition

Hereditary elliptocytosis is a disorder passed down through families in which the red blood cells are abnormally shaped. It is similar to other blood conditions such as hereditary spherocytosis and hereditary ovalocystosis.

Causes

Elliptocytosis affects about 1 in every 2,500 people of northern European heritage. It is more common in people of African and Mediterranean descent. You are more likely to develop this condition if someone in your family has had it.

Symptoms

Symptoms may include:

Exams and Tests

An exam by your health care provider may show an enlarged spleen.

The following test results may help diagnose the condition:

Treatment

There is no treatment needed for the disorder unless severe anemia or anemia symptoms occur. Surgery to remove the spleen may decrease the rate of red blood cell damage.

Outlook (Prognosis)

Most people with hereditary elliptocytosis have no problems. They often do not know they have the condition.

Possible Complications

Elliptocytosis is often harmless. In mild cases, fewer than 15% of red blood cells are elliptical-shaped. However, some people may have crises in which the red blood cells rupture. This is more like to happen when they have a viral infection. People with this disease can develop anemia, jaundice, and gallstones.

When to Contact a Medical Professional

Call your provider if you have jaundice that does not go away or symptoms of anemia or gallstones.

Prevention

Genetic counseling may be appropriate for people with a family history of this disease who wish to become parents.


Review Date: 1/19/2018
Reviewed By: Richard LoCicero, MD, private practice specializing in hematology and medical oncology, Longstreet Cancer Center, Gainesville, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

This information should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. © 1997- 2007 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.