Alpha fetoprotein

Definition

Alpha fetoprotein (AFP) is a protein produced by the liver and yolk sac of a developing baby during pregnancy. AFP levels go down soon after birth. It is likely that AFP has no normal function in adults.

A test can be done to measure the amount of AFP in your blood.

How the Test is Performed

A blood sample is needed. Most of the time, blood is typically drawn from a vein located on the inside of the elbow or the back of the hand.

How to Prepare for the Test

You do not need to take any special steps to prepare.

How the Test will Feel

You may feel slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn.

Why the Test is Performed

Your health care provider may order this test to:

Normal Results

The normal values in males or nonpregnant females is generally less than 40 micrograms/liter.

The examples above are common measurements for results of these tests. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

Greater than normal levels of AFP may be due to:


Review Date: 8/26/2017
Reviewed By: Peter J Chen, MD, FACOG, Associate Professor of OBGYN at Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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