Ureteral retrograde brush biopsy is a surgical procedure. During the surgery, your surgeon takes a small sample of tissue from the lining of the kidney or ureter. The ureter is the tube that connects a kidney to the bladder. The tissue is sent to a lab for testing.
This procedure is done using:
You will not feel any pain. The test takes about 30 to 60 minutes.
A cystoscope is first placed through the urethra into the bladder. Cystoscope is a tube with a camera on the end.
The sample is then sent to a pathology lab for analysis. The instrument and guide wire are removed from the body. A small tube or stent may be left in the ureter. This prevents a kidney blockage caused by swelling from the procedure. It is removed later.
You may not be able to eat or drink anything for about 6 hours before the test. Your health care provider will tell you how you need to prepare.
You may have some mild cramping or discomfort after the test is over. You may have a burning feeling the first few times you empty your bladder. You may also urinate more often or have some blood in your urine for a few days after the procedure. You may have discomfort from the stent that will continue to be in place until it is removed at a later time.
This test is used to take a sample of tissue from the kidney or ureter. It is performed when an x-ray or other test has shown a suspicious area (lesion). This can also be done if there is blood or abnormal cells in the urine.
The tissue appears normal.
Abnormal results may show cancer cells (carcinoma). This test is often used to tell the difference between cancerous (malignant) and noncancerous (benign) lesions.
Risks for anesthesia and surgery in general are:
Another possible risk for this procedure is a hole (perforation) in the ureter. This can cause scarring of the ureter and you may need another surgery to correct the problem. Tell your provider if you have an allergy to seafood. This could cause you to have an allergic reaction to the contrast dye used during this test.
This test should not be performed in people with a:
You may have abdominal pain or pain on your side (flank).
A small amount of blood in the urine is normal the first few times you urinate after the procedure. Your urine may look faintly pink. Report very bloody urine or bleeding that lasts longer than 3 emptyings of the bladder to your provider.
Call your provider if you have:
Reviewed By: Sovrin M. Shah, MD, Assistant Professor, Department of Urology, The Icahn School of Medicine at Mount Sinai, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.