Lipoproteins are molecules made of proteins and fat. They carry cholesterol and similar substances through the blood.
A blood test can be done to measure a specific type of lipoprotein called lipoprotein-a, or Lp(a). A high level of Lp(a) is considered a risk factor for heart disease.
A blood sample is needed.
You will be asked not to eat anything for 12 hours before the test.
DO NOT smoke before the test.
A needle is inserted to draw blood. You may feel slight pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.
High levels of lipoproteins can increase the risk for heart disease. The test is done to check your risk for atherosclerosis, stroke, and heart attack.
It is not yet clear if this measurement leads to improved benefits for patients. Therefore, many insurance companies DO NOT pay for it.
The American Heart Association and American College of Cardiology DO NOT recommend the test for most adults who DO NOT have symptoms. It may be useful for people at higher risk because of a strong family history of cardiovascular disease.
Normal values are below 30 mg/dL (milligrams per deciliter), or 1.7 mmol/L.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The example above shows the common measurements for results of these tests. Some laboratories use different measurements or may test different specimens.
Higher than normal values of Lp(a) are associated with a high risk for atherosclerosis, stroke, and heart attack.
Lp(a) measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a standard lipid panel is unknown.
Reviewed By: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.